
尹烨, 哥本哈根大学博士,基因组学研究员,大连理工大学兼职教授 , 第三届中国人类遗来自传资源管理专家组成员 ,中国计量测试学会生物计量专业委员会委员 ,中国抗癌协会肿瘤科普片防治专业委员会常务委员 ,第四批国家"万人计划"科技创业领军人360百科才 ,第二届广东十大科学传播达人 ,深圳市标准化协会难附甚显井销第七届理事会会长 。
他热爱生命科学,做研究、形司就概氢威核发论文、惜人才、重团队,曾任华大科技总裁、华大集团首席运营官(COO)、华大医学总裁。
他是"非既吸烈备免典"科研攻关主要参与者之一 ,曾当选最年轻的中国杰出质量人 、华大基因全球化布局推动者、华大基因收静掌介践试购CG项目核心成员 、率领华大基因成功登陆创业板 。
2018年1月,他在JP Morgan会议上率先发布个人全基因组测序正式进入百元美金时代、同时发布解密所有5000种哺乳动物基因组的"生命周期表计划" 。
他心系公益事业 ,组建面向罕见病群体的机构"同病相联",和团队一起成立救助遗传病的"华基金""光基金" ,带领团队发起多项罕见病救助计划 ,获夜厂白给毫并主导"科技援藏暨超低女进言担班尔材笑温冰箱运送活动" 。
他是媒体圈、财经圈、科研圈最受欢迎的生物界"名嘴",也是传播器汉候们生命科学的科普工作者 。开设"天方烨谈" 电台节目,受邀出席WIRED、TEDx、一席、中国企业家论坛等媒体活动发矿无第露,为大众讲述"听得懂的生命科学"。
- 中文名称 尹烨
- 国籍 中国
- 民族 满族
- 出生日期 1979年
- 出生地 辽宁丹东
人物简介
尹烨2002年加入华大基因分支--北京华大吉比爱生物技术有限公司,先后从事体外诊断试剂研发、产品注册、生产管理、质量管理、市场营销等工作,在生物产品研发、生产、质控、申报注册及生物技术临床应用推广等方面秋娘东兴坐有丰富的经验,主持申报多来自项专利,数十项体外诊断试剂,对于GMP/I360百科VD/ISO系列质量管理体系有深刻理解。2003年春,尹烨作为"非典型性肺炎"早期诊断科研攻关的主要参与者之一,在华大高效完成SARS病毒测短船台音市染止鲁曲序和获得诊断蛋白之后,他率领团队在24小时内即完成了SARS诊断试剂盒全部研发根委及申报材料的准备并顺风黄念划刑例影继油派利获得了国药局的审批。随后,华大及时将30万人份"免疫检测试剂盒"免费送到了防治SARS的第一线。

2009年,因综合表现突出,尹烨调入华大基因总部,负责基因组学承意不划绍及生物信息学全球范围内的产业推广,并先后出任华大基因科技合作事业前适被临令易部总裁、全球生产平台负责人、华既维大基因研究院助理院长 ,华大集团首席运营官 ,华大医学执行总裁等职 。他负责组建起华大基因全球营销团队,打造华大基因全球化科研、产业平台,完成了华大的全球化布局。期间,尹烨先后担任全球"千种动植物基因组计划"总指挥,"百万人重测序计划"第一负责人,"蒙古高原特色物种基因组计划"总负责人,"蒙古族人基因组计划"项目主持人等,主持或参与了上百个国际基因组合作项目,在Nature等国际顶级学术期刊发表多篇论文,并推进建立华大与全球生物科研机构良好合作关系,处为推动基因组学研究、分子育种、医疗健康、环境能源等领域的科研发展及为广大普通民众提供前沿生物科技在医疗、农业、环境及能源等领域的老社想取准可阿季相客校应用服务做出重要贡献来求学因肥句评婷。在任华大医学执行总裁期间,全面贯彻个体化、预测、干预、参与"4P医学"理念,推动了基因检测的临床应用发展,以降低出生缺陷及重大疾病对人类健康的危害。
华大基因在2013年成功完成对美国上市公司Complete G敌子老进立家静进enomics的全资收购,尹烨 在华大此次海外收购过程中作为核心成员起到了关键作用,积累了丰富的资本运作和融投资经验。
目前,尹烨任华大基因股份有限公司CEO ,率领团队积极推动前沿生物技术和基因组学研究成果的产业化 应用,向全球顶尖的医疗机构、科研机构、大学、药厂、育种公司等提供完整的基因组学解决方案,为临床行为提供诊断、干预和治疗依据,为生命科学及当克格医学创新提供技术和研究服务,致力于成为全球基因科技应用服务行业领导者。
尹烨心系公益事业 ,他长期支持中国渐加临用酒报又旧罕见病发展中心等罕见病专服使大李审尽业组织 ,发起并组建"同并相联"网站,以期打造成为罕见病 、遗传病诊治与交流第一平台。他亦发起成立"爱之光眼病基因检测 " 专项基金。
而 同时他还经常投身公益盟活动,多次发起如"子琪计划" (针对粘多糖病救助)、"春叔计划" (支持造血干细胞行动)、"晓明计划" (针对入守缺文费鱼鳞病救助) 项目、"阳光计划" (免费为深圳重型地中海贫血家庭配型)等活动。
获奖记录
20管乐有沉沿族排市盾17年5月获评十大"深圳好青年"
2017年1月获"2017年度公益人物奖"
2016年12月获"中国杰出质量人(全国质量奖个人奖)"
2016年11月获"2016时代深士"称号
2015年11月被大连理工大学聘请为兼职教授。
2015年获评大连理工大学"2014校友年度人物"青年校友成就奖
2014年获中国十大经济潮流人物奖
主要论子息然具文
- Wang X, Wang H, Wang J,…, Yin Y…, Brassica rapa Genome Sequencing Project Consortium. (2011) The genome of the 来自mesopolyploid crop species Brassica rap360百科a. Nature Geneti位与cs. 2011 Aug 28;43(10):1035-9.
- 岳桂东,高强,罗龙海,王军一,许娇卉,尹烨 (2012) 高通量测序技术在动植物研究领域中的应用.知新密台大交即训皇鲁中国科学,42(2): 107-124.
- Gao Q, Yue GD, L市建聚充现护粮笔效拿种i WQ, Wang JY, Xu JH, Yin Y. (2012) Recent progress using high-throughput sequencing technologies in plant molecular breeding. Journal of Integrative Plant Biology, 54(4):215-27.
- Qiu Q, Zhang G, Ma T,…, Yin Y, …明.(2012) The yak 子流婷安他八穿较袁genome and adaptation to life at 吃究引high altitude. Nature Ge香日期散变受netics. 2012 Jul 1农位庆;44(8):946-9.
- Kunbo Wang, Zhiwen Wang日露散也血, Fuguang Li, …, Ye Yin,…. (2012) The draft gen后鲁品经况划律ome of a diploid cotton Gossypium raimondii. Nature Genetics. 2012 Aug 26; 44(10):1稳可纸附务向探模注样098–1103
- Zhang G, Fang X, Guo X, …, Yin Y, Wang J. (2012) The oyster genome reveals stress adaptation and complexity of shell formation.Nature. 2012 Oct 4;490(7418):49-54.
- David M A破行胡业西包置ltshuler, Richard M Durbin, Goncalo R Abecasis...Yin Y...(2012)An integrated map of gene师些专与青并放tic variati结on from 1,092 human genomes. Nature. 2012 November 1; 491(7422): 56–65.
- S天夫独haogui Guo, Jianguo Zhang, Honghe Sun, …, Ye Yin, ….(2012) The draft genome of watermelon (Citrullus lanatus建措) and resequencing of 20 diverse accessions. Nature Genetics. 2012 Nov 25; 45(1):51–58
- Yin Y, Yue GD, Gao Q, Wang ZY,... (2012) Genome Sequenc松座甲地十又神普积审画e of Pedobacter arcticus sp. nov., a Sea Ice Bacterium Isolated from Tundra Soil. Journal of Bacteriology, 2012 Dec;194 (23):6688.
- Qixiang Zhang, Wenbin Chen, Lidan Sun, …,Ye Yin, …(2012) The genome of Prunus mume.Nature Communications, 2012,DOI: 10.1038/ncomms2290
- Xiangjiang Zhan, Shengkai Pan, Junyi Wang, …, Ye Yin, …(2013) Peregrine and saker falcon genome sequences provide insights into evolution of a predatory lifestyle.Nature Genetics. 2013 March 24;45(5): 563–566
- Zhuo Wang, Juan Pascual-Anaya, Amonida Zadissa,…, Ye Yin, Bronwen Aken, Guojie Zhang& Naoki Irie.(2013) The draft genomes of soft-shell turtle and green sea turtle yield insights into the development and evolution of the turtle-specific body plan. Nature Genetics. 2013 April28;10.1038/ng.2615
- Jinfeng Chen, Quanfei Huang, Dongying Gao...Ye Yin...(2013)Whole-genome sequencing of Oryza brachyantha reveals mechanisms underlying Oryza genome evolution. Nature Communications, 2013, DOI: 10.1038/ncomms2596
- Yabin Chen, Qingyan Zhang,Tao Shen … ,Ye Yin, …. (2013)Comprehensive mutation analysis by whole-exome sequencing in 41 Chinese families with Leber congenital amaurosisInvest . Ophthalmol Vis Sci. 2013 May 9(共同作者)
- Huang L1, Zhang Q, Li S, Guan L, Xiao X, Zhang J, Jia X, Sun W, Zhu Z, Gao Y, Yin Y, Wang P, Guo X, Wang J, Zhang Q.(2013) Exome sequencing of 47 chinese families with cone-rod dystrophy: mutations in 25 known causative genes. PLoS One. 2013 Jun 11; 8(6):e65546.
- Xiaosen Guo, Max Brenner, Xuemei Zhang, ..., Ye Yin, ... (2013) Whole-Genome Sequences of DA and F344 Rats with Different Susceptibilities to Arthritis,Autoimmunity, Inflammation and Cancer. Genetics, August 2013, 194(4):1017-28
- Zhang C1, Li D, Zhang J,..., Yin Y, ....(2013)Mutations in ABCB6 cause dyschromatosis universalis hereditaria. J Invest Dermatol. 2013 Sep;133(9):2221-8.
- Tao Ma,Junyi Wang,Gongke Zhou, … ,Ye Yin, …(2013) Genomic insights into salt adaptation in a desert poplar. Nature Communications,2013, doi:10.1038/ncomms3797.
- Xiao JH, Yue Z, Jia LY, ..., Yin Y...(2013)Obligate mutualism within a host drives the extreme specialization of a fig wasp genome. Genome Biology,2013,14:R141 doi:10.1186
- Cheng Qin, Changshui Yu, Yaou Shen, …, Ye Yin, Jiping Yu, Kailin Hu, and Zhiming Zhang.(2014) Whole-genome sequencing of cultivated and wild peppers provides insights into Capsicum domestication and specialization. PANS, 2014,doi/10.1073/pnas.1400975111
- Udpa N, Ronen R, Zhou D,..., Yin Y...(2014)Whole genome sequencing of Ethiopian highlanders reveals conserved hypoxia tolerance genes. Genome Biology. 2014 Feb 20;15(2):R36.
- Shiqiang Li, Liping Guan, Shaohua Fang, ..., Ye Yin, ...(2014) Exome sequencing reveals CHM mutations in six families with atypical choroideremia initially diagnosed as retinitis pigmentosa. International Journal of Molecular Medicine,2014 June 6, DOI: 10.3892
- Xu Y1, Guan L, Shen T, ..., Yin Y, Guo X, Wang J, Zhang Q.(2014) Mutations of 60 known causative genes in 157 families with retinitis pigmentosa based on exome sequencing. Hum Genet. 2014 Jun 18.
- Su Z, Labaj PP, Li S, ..., Yin Y, ... (2014) A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium. Nature Biotechnology. 2014 Sep; 32(9):903-14.
- Xinfen Yu, Tao Jin, Yujun Cui, ..., Ye Yin, ...(2014) Coexistence of influenza H7N9 and H9N2 in poultry linked to human H7N9 infection and their genome characteristics. journal of Virology. 2014 Mar, 88(6):3423-31.
- Huiguang Wu, Xuanmin Guang, Mohamed B. Al-Fageeh...Ye Yin,...(2014)Camelid genomes reveal evolution and adaptation to desert environments. Nature Communications. 21 October 2014, doi:10.1038/ncomms6188
- Haihua Bai, Xiaoshen Guo, Dong Zhang, ... Ye Yin,...(2014)The genome of a mongolian individual reveals the genetic imprints of mongolians on modern human populations.Genome Biology and Evolution. 5 November 2014, 6(12):3122-3136
- Xiangyu Ma, Liping Guan, Wei Wu,...Ye Yin, ...(2015) Whole-exome sequencing identifies OR2W3 mutation as a cause of autosomal dominant retinitis pigmentosa. Scientific Report. 2015 Mar 18;5:9236. doi: 10.1038/srep09236.
- Zhang H1, Gao Y, Jiang F,...Yin Y,...(2015)Non-invasive prenatal testing for trisomies 21, 18 and 13: clinical experience from 146 958 pregnancies. Ultrasound Obstet Gynecol. 2015; 45: 530–538Published online 8 April 2015 in Wiley Online Library . DOI:10.1002/uog.14792.
- Wang J, Wen J, Li J,...Yin Y,...(2003) Assessment of immunoreactive synthetic peptides from the structural proteins of severe acute respiratory syndrome coronavirus. Clinical Chemistry. 2003 Dec;49(12):1989-96.
- Khurana E, Fu Y, Colonna V,...Yin Y,... (2013) Integrative annotation of variants from 1092 humans: application to cancer genomics. Science. 2013 Oct 4;342(6154):1235587. doi: 10.1126/science.1235587.
- Yu X, Jin T, Cui Y,...Yin Y,... (2014) Influenza H7N9 and H9N2 viruses: coexistence in poultry linked to human H7N9 infection and genome characteristics. Journal of Virology. 2014 Mar;88(6):3423-31. doi: 10.1128/JVI.02059-13. Epub 2014 Jan 8.
- Huerta-Sánchez E, Jin X, Asan,...Yin Y,... (2013) Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA. Nature. 2014 Aug 14;512(7513):194-7. doi: 10.1038/nature13408. Epub 2014 Jul 2.
- Cai N, Chang S, Li Y1,...Yin Y,... (2015) Molecular signatures of major depression. Current Biology.2015 May 4;25(9):1146-56. doi: 10.1016/j.cub.2015.03.008. Epub 2015 Apr 23.
- Bäckhed F, Roswall J, Peng Y,...Yin Y,... (2015) Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life. Cell Host Microbe. 2015 May 13;17(5):690-703. doi: 10.1016/j.chom.2015.04.004.
- Xu Y, Guan L, Xiao X,...Yin Y,... (2015) Mutation analysis in 129 genes associated with other forms of retinal dystrophy in 157 families with retinitis pigmentosa based on exome sequencing. Molecular Vision. 2015 Apr 28;21:477-86. eCollection 2015.
- Xu Y, Guan L, Xiao X,...Yin Y,... (2015) ALMS1 null mutations: a common cause of Leber congenital amaurosis and early-onset severe cone-rod dystrophy. Clinical Genetics. 2015 May 22. doi: 10.1111/cge.12617.
- Zhang W, Yu Y, Hertwig F,...Yin Y,... (2015)Comparison of RNA-seq and microarray-based models for clinical endpoint prediction.Genome Biology. 2015 Jun 25;16:133. doi: 10.1186/s13059-015-0694-1.
- Li J, Gao B, Guan L,...Yin Y,... (2015) Unique Variants in OPN1LW Cause Both Syndromic and Nonsyndromic X-Linked High Myopia Mapped to MYP1. Investigative Ophthalmology & Visual Science. 2015 Jun;56(6):4150-5. doi: 10.1167/iovs.14-16356.
- Cai N, Bigdeli TB, Kretzschmar W,...Yin Y,... (2015) Sparse whole-genome sequencing identifies two loci for major depressive disorder.Nature. 2015 Jul 30;523(7562):588-91. doi: 10.1038/nature14659. Epub 2015 Jul 15.
- Zhang X, Zhang D, Jia H,...Yin Y,... (2015) The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment.Nature Medicine.2015 Aug;21(8):895-905. doi: 10.1038/nm.3914. Epub 2015 Jul 27.
- 1000 Genomes Project Consortium, Auton A, Brooks LD... (2015) A global reference for human genetic variation. Nature. 2015 Oct 1;526(7571):68-74. doi: 10.1038/nature15393.
- Sudmant PH, Rausch T, Gardner EJ,...Yin Y,... (2015)An integrated map of structural variation in 2,504 human genomes. Nature. 2015 Oct 1;526(7571):75-81. doi: 10.1038/nature15394.
- Li C, Gao Z, Li F, Li X,...Yin Y,... (2015) Whole Exome Sequencing Identifies Frequent Somatic Mutations in Cell-Cell Adhesion Genes in Chinese Patients with Lung Squamous Cell Carcinoma.Scientific Reports.2015 Oct 27;5:14237. doi: 10.1038/srep14237.
- Xu Y1, Guan L, Xiao X,...Yin Y,... (2015) Identification of MFRP Mutations in Chinese Families with High Hyperopia. Optometry & Vision Science.2016 Jan;93(1):19-26. doi: 10.1097/OPX.0000000000000751.
- Delaneau O, Marchini J; 1000 Genomes Project Consortium.(2014) Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel.Nature Communications.2014 Jun 13;5:3934. doi: 10.1038/ncomms4934.
- Colonna V, Ayub Q, Chen Y,...1000 Genomes Project Consortium,... (2014) Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences.Genome Biology.2014 Jun 30;15(6):R88. doi: 10.1186/gb-2014-15-6-r88.
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